Question
For each of the following study outcomes, propose a possible method for validation.
In a study of the effect of a new drug for lowering blood pressure, investigators asked patients to self-report the blood pressure reading from their last visit to a primary care physician.
Investigators are testing the effectiveness of a new drug for treating childhood cases of malaria; however, they’re concerned that it may cause side effects. Investigators asked children to self-report their side effects during weekly study visits.
A cluster-randomized control trial is occurring in a country with universal healthcare. Study investigators are interested in the effects of their intervention on reducing cardiovascular events, and rely on clinicians to report events to study investigators.
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