Question
An investigator is interested in studying the effect of a new treatment for preventing the transmission of HIV from mother to infant during childbirth. Explain why each of the below mentioned eligibility criteria may have been deemed necessary:
Only HIV-infected pregnant women are included
Women are excluded if the fetus had an anomaly that would increase the concentration of a metabolite of the drug that would endanger its health.
Women with a immediate medical need for anti-retroviral medication are excluded.
Source: Maximo wrote question based on Chapter 7 of Ashengrau and Seage page 183
